Work

Author response: Protomer alignment modulates specificity of RNA substrate recognition by Ire1

Year: 2021

Type: peer-review

Abstract: Biochemical analysis and computational modeling reveal how cells mechanistically control the quality of their proteomes and demonstrate that the precise alignment of subunits in oligomeric complexes can profoundly affect enzymatic properties.

DOI: 10.7554/elife.67425.sa2

Authors: Weihan Li, Kelly Crotty, Diego Garrido Ruiz, Mark Voorhies, Carlos Rivera, Anita Sil, R Dyche Mullins, Matthew P Jacobson, Jirka Peschek, Peter Walter

Institutions: Howard Hughes Medical Institute, University of California, San Francisco, Yale University

Language: English

Topic: Endoplasmic Reticulum Stress and Disease

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W3163350366

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