Fiber endface photoacoustic generator for quantitative photoacoustic tomography
Year: 2021
Type: article
Abstract: We demonstrate a novel fiber endface photoacoustic (PA) generator using infrared (IR) 144 laser dye dispersed within an ultraviolet adhesive. The generator provides a wide acoustic bandwidth in the transducer frequency range of 2-7 MHz, high thermal conversion efficiency (${\gt}90\%$), good PA signal controllability (well-controlled IR 144 concentration), and high feasibility (simple procedures). Through a series of experimental validations, we show that this fiber-based endface PA generator can be a useful tool for a broad range of biomedical applications such as calibrating the local absorption coefficient of biological tissue for quantitative PA tomography.
Source: Optics Letters
DOI: 10.1364/ol.426033
Institution: Washington University in St. Louis
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
Funder: National Cancer Institute
Awards: G3178261572, G5235292164
OpenAlex ID: W3163379429
