Work

Single cell and spatial transcriptomics in human tendon disease indicate dysregulated immune homeostasis

Year: 2021

Type: article

Abstract: signal in tender vs non-tender non-swollen wrists.inflammatory activation of pain fibres might not yet be an issue.A limitation of this study is the evaluation of tenderness by Ritchie Articular Index, reducing the number of joint areas available for analysis.The pathophysiology behind a tender joint in early RA should be further explored, and joint tenderness might deserve more attention when aiming for remission in early disease.

Source: Annals of the Rheumatic Diseases

DOI: 10.1136/annrheumdis-2021-220256

Authors: Moeed Akbar, Lucy MacDonald, Lindsay A N Crowe, Konstantin Carlberg, Mariola Kurowska-Stolarska, Patrik L Ståhl, Sarah J B Snelling, Iain B McInnes, Neal L Millar

Institutions: University of Glasgow, Science for Life Laboratory, KTH Royal Institute of Technology, University of Oxford

Language: English

Topic: Tendon Structure and Treatment

Subfield: Orthopedics and Sports Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,870

Funders: Amgen, Eli Lilly and Company, Pfizer, AstraZeneca, Gilead Sciences, Celgene, Mylan, Astellas Pharma, Norges Forskningsråd, Norske Kvinners Sanitetsforening, Norsk Revmatikerforbund, Medical Research Council, Helse Sør-Øst RHF, UCB Pharma

Awards: Damage mechanisms in tendon disease, G6318752936

OpenAlex ID: W3163438330

FWCI: 11.5

Cites: 9

Cited by: 79

Related to: 10