Work

Design, Synthesis, and Structure–Activity Relationship of N-Aryl-N′-(thiophen-2-yl)thiourea Derivatives as Novel and Specific Human TLR1/2 Agonists for Potential Cancer Immunotherapy

Year: 2021

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.0c02266

Authors: Zhipeng Chen, Lina Zhang, Junjie Yang, Lu Zheng, Fanjie Hu, Siqin Duan, Kutty Selva Nandakumar, Shuwen Liu, Hang Yin, Kui Cheng

Institutions: Southern Medical University, Center for Life Sciences, Tsinghua University

Language: English

Topic: Immune Response and Inflammation

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province, Guangdong Medical Research Foundation, Guangzhou Science and Technology Program key projects

Awards: G3798115415, G43929437, G5520126173, G637268881, G6999500398, G7216227037, G7221384277, G8608118393

OpenAlex ID: W3164541967

FWCI: 2.794

Cites: 34

Cited by: 46

Related to: 10