Work

GRSF1 deficiency in skeletal muscle reduces endurance in aged mice

Year: 2021

Type: article

Abstract: mRNAs, were significantly elevated in aged Grsf1cKO muscle. Our findings suggest that GRSF1 deficiency exacerbates the functional decline of aged skeletal muscle, likely through multiple downstream effector proteins.

Source: Aging

DOI: 10.18632/aging.203151

Authors: Riley K. Driscoll, Linda K. Krasniewski, Samuel G. Cockey, Jen-Hao Yang, Yulan Piao, Elin Lehrmann, Yongqing Zhang, Marc Michel, Ji Heon Noh, Chang-Yi Cui, Myriam Gorospe

Institutions: National Institutes of Health, National Institute on Aging, Chungnam National University

Language: English

Topic: Muscle Physiology and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: National Institute on Aging

OpenAlex ID: W3164613509

FWCI: 0.628

Cites: 33

Cited by: 6

Related to: 10