Work

N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation

Year: 2021

Type: article

Source: Cancer Cell

DOI: 10.1016/j.ccell.2021.04.017

Authors: Yuanming Cheng, Wei Xie, Brian F. Pickering, Karen L. Chu, Angela M. Savino, Xuejing Yang, Hanzhi Luo, Diu TT. Nguyen, Shanlan Mo, Ersilia Barin, Anthony Velleca, Thomas M. Rohwetter, Dinshaw J. Patel, Samie R. Jaffrey, Michael G. Kharas

Institutions: Memorial Sloan Kettering Cancer Center, Cornell University, Weill Cornell Medicine, Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology

Language: English

Topic: RNA modifications and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Alex's Lemonade Stand Foundation for Childhood Cancer, Leukemia and Lymphoma Society, New York State Stem Cell Science, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke

Awards: The role of the Musashi family in hematopoiesis, Identification of therapeutic targets for leukemia stem cells in AML-iPSC models, G2820883399, G3122084441, G3252671852, G3922416087, G4107684628, G5561857075, G653601094, G7024943315, G7406459668, Cancer Center Support Grant, New mechanisms and technologies for understanding post-transcriptional gene regulation in neurons

OpenAlex ID: W3164912031

FWCI: 11.38

Cites: 56

Cited by: 246

Related to: 10