Work

DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner

Year: 2021

Type: article

Source: Acta Neuropathologica

DOI: 10.1007/s00401-021-02333-z

Authors: Tyler R. Fortuna, Sukhleen Kour, Eric N. Anderson, Caroline Ward, Dhivyaa Rajasundaram, Christopher J. Donnelly, Andreas Hermann, Hala Wyne, Frank Shewmaker, Udai Bhan Pandey

Institutions: University of Pittsburgh, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, German Center for Neurodegenerative Diseases, Universitätsmedizin Rostock, University of Rostock, Uniformed Services University of the Health Sciences

Language: English

Topic: Amyotrophic Lateral Sclerosis Research

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute on Aging, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke

Awards: Mechanisms of C9orf72-associated dipeptide toxicity, Cellular and Molecular Mechanisms of FUS-related ALS/FTD, Molecular mechanisms of C9orf72 and Matrin 3 interaction in ALS, An optogenetic approach to establish the interplay between stress granules and TDP-43 proteinopathy in ALS/FTD, Targeting epigenetic modifiers of androgen receptor activity and toxicity in SBMA, Using naturally-occurring fungal prions as models of neurodegenerative protein misfolding, Drosophila models for ubiquilin-associated ALS, Oligonucleotide approach to antagonize neurotoxic TDP-43 assemblies in dementia

OpenAlex ID: W3165762517

FWCI: 2.509

Cites: 107

Cited by: 29

Related to: 10