Work

Author response: Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates

Year: 2021

Type: peer-review

Abstract: MRGPRD and MRGRPX1 are co-expressed in primate DRG neurons, but β-alanine and BAM8-22, preferentially activate CMH-subclasses, and co-activating different cutaneous nociceptors by pruritogens does not change itch sensation to pain.

DOI: 10.7554/elife.64506.sa2

Authors: Amanda Klein, Hans Jürgen Solinski, Nathalie M Malewicz, Hada Fong-ha Ieong, Elizabeth I Sypek, Steven G Shimada, Timothy V Hartke, Matthew Wooten, Gang Wu, Xinzhong Dong, Mark A Hoon, Robert H LaMotte, Matthias Ringkamp

Institutions: University of Minnesota, Johns Hopkins University, Heidelberg University, National Institute of Dental and Craniofacial Research, Medizinische Fakultät Mannheim, Yale University, BG University Hospital Bergmannsheil Bochum, Ruhr University Bochum, Howard Hughes Medical Institute

Language: English

Topic: Pain Mechanisms and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

OpenAlex ID: W3166187909

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