Work

Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy

Year: 2021

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2021.113579

Authors: Satish Sagar, Sarbjit Singh, Jayapal Reddy Mallareddy, Yogesh A. Sonawane, John V. Napoleon, Sandeep Rana, Jacob I. Contreras, Christabelle Rajesh, Edward L. Ezell, Smitha Kizhake, Jered C. Garrison, Prakash Radhakrishnan, Amarnath Natarajan

Institutions: Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center

Language: English

Topic: NF-κB Signaling Pathways

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Cancer Institute

Awards: G2364899322, G3373492060, G824925878, Development of Quinoxaline Based IKKbeta Inhibitors for Kras Driven Cancers, Buffett Cancer Center Support Grant

OpenAlex ID: W3166770092

FWCI: 1.07

Cites: 62

Cited by: 17

Related to: 10