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First-in-human biomarker-driven phase I trial of the potent and selective glutaminase-1 (GLS1) inhibitor IACS-6274 (IPN60090) in patients (pts) with molecularly selected advanced solid tumors.

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Year: 2021
Type: conference-abstract
Source: Journal of Clinical Oncology
DOI: 10.1200/jco.2021.39.15_suppl.3001
Authors: Timothy A. Yap, Ecaterina Elena Dumbrava, Jordi Rodon Ahnert, David S. Hong, Shubham Pant, Daniel D. Karp, Sarina Anne Anne Piha-Paul, Vivek Subbiah, Apostolia Maria Tsimberidou, Siqing Fu, Filip Janku, Sandra Montez, Majd T Ahmad-Taha, Darlene Guerrero, Natalya N. Nazarenko, Yan Moore, Michael Soth, Jeff Kovacs, Timothy P. Heffernan, Philip Jones
Institution: The University of Texas MD Anderson Cancer Center
Language: English

Topic: Cancer, Hypoxia, and Metabolism
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funder: University of Texas MD Anderson Cancer Center
OpenAlex ID: W3170159148
Cites:
Cited by: 22
Related to: 10
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