Impact of Antiretroviral Treatment on the Plasmatic Viral Load of HIV-1 in Children Followed at the Charles de Gaulle Pediatric University Hospital (CHU-CDG), Ouagadougou Burkina Faso
Year: 2021
Type: article
Study design: Observational Study
Abstract: Introduction: Despite the improvement in the coverage and effectiveness of Prevention of Mother-to-Child Transmission of HIV (PMTCT) interventions, the pediatric epidemic of HIV infection still persists and the number of PLWHIV in Burkina Faso is estimated at the end of 2018 at 94,000, including 9,400 children under 15 years old.Objective: The objective of this work is to contribute to better medical care for children under-15 living with HIV-1 by studying the impact of ART on virus replication, through the measurement of viral load ( VL).Methodologies: This was a retrospective descriptive study carried out at Pediatric University Hospital Charles-de-Gaulle from January 1, 2016 to June 30, 2019.The study included all children under-15 infected with HIV type 1 (HIV-1) and with a plasma viral load measured in the Bacteriology-Virology Department during the study period.Results: Out of a total of 811 children, 51% were boys, i.e. a sex ratio of 1.03 and nearly 80% of our patients came from the ESTHER project.The most represented age group was [10 -15] years (50.06%).Among children, 47.3% had a treatment duration greater than or equal to 4 semesters and 43.2% had an undetectable plasma viral load after 4 semesters.
Source: ACTA SCIENTIFIC MICROBIOLOGY
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3170484123