Work

Author response: Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients

Year: 2021

Type: peer-review

Abstract: A 3D bone marrow niche that reproduces megakaryocyte differentiation and ex vivo platelet production from hematopoietic progenitors and iPSCs of thrombocytopenic patients predicts individual response to Eltrombopag accurately.

DOI: 10.7554/elife.58775.sa2

Authors: Christian A Di Buduo, Pierre-Alexandre Laurent, Carlo Zaninetti, Larissa Lordier, Paolo M Soprano, Aikaterini Ntai, Serena Barozzi, Alberto La Spada, Ida Biunno, Hana Raslova, James B Bussel, David L Kaplan, Carlo L Balduini, Alessandro Pecci, Alessandra Balduini

Institutions: University of Pavia, Policlinico San Matteo Fondazione, Université Paris-Sud, Inserm, Université Paris-Saclay, La Ligue Contre le Cancer, Institute of Genetic and Biomedical Research, National Research Council, Weill Cornell Medicine, Tufts University

Language: English

Topic: Platelet Disorders and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W3170665609

Cites: 47

Cited by:

Related to: 10