Author response: The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel
Year: 2021
Type: peer-review
Abstract: Substrate-induced structural changes in GtACR1 provide new insight into the chemical mechanism of natural light-gated anion conductance and facilitate its optimization for photoinhibition of neuron firing in optogenetics.
Institutions: Paul Scherrer Institute, Swiss Light Source, Boston University
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W3172313529