Associations of Binge Drinking With Vascular Brain Injury and Atrophy in Older American Indians: The Strong Heart Study
Year: 2021
Type: article
Study design: Observational Study
Abstract: Objectives: American Indians (AIs) generally consume less alcohol than the US general population; however, the prevalence of alcohol use disorder is higher. This is the first large cohort study to examine binge drinking as a risk factor for vascular brain injury (VBI). Methods: We used linear and Poisson regression to examine the association of self-reported binge drinking with VBI, measured via magnetic resonance imaging (MRI), in 817 older AIs who participated in the Strong Heart and Cerebrovascular Disease and Its Consequences in American Indians studies. Results: Any binge drinking at multiple time-points was associated with increased sulcal (β = 0.360, 95% CI [0.079, 0.641]) and ventricle dilatation (β = 0.512, 95% CI [0.174, 0.850]) compared to no binge drinking. Discussion: These observed associations are consistent with previous findings. Identifying how binge drinking may contribute to VBI in older AIs may suggest modifiable health behaviors for neurological risk reduction and disease prevention.
Source: Journal of Aging and Health
Institutions: University of Alaska Anchorage, Washington State University, Oklahoma State University Center for Health Sciences, Howard University, Georgetown-Howard Universities Center for Clinical and Translational Science, MedStar Health Research Institute, University of Washington, University of Colorado Anschutz
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G1054613177, Cardiovascular Disease in Sioux Indians, G1108064970, G1368423069, The Strong Heart Study, Phase V, G164614106, CVD in American Indians Biomarker lab and Arizona Field Center, G2459777474, G2968741700, G2984989008, G305513510, G3191277318, American Indian and Alaska Native Health Disparities, G3944366851, CVD in American Indians Genetics Center, G4289235060, CVD in American Indians Study and Data Management Center and OK Field Center, G4756503958, G488839146, G6412155744, G75289209, CVD in American Indians The Dakota Field Center, G863538970, University of Washington Alzheimer's Disease Research Center
OpenAlex ID: W3173406957