Work

TheToxoplasmaPolymorphic Effector GRA15 Mediates Seizure Induction by Modulating Interleukin-1 Signaling in the Brain

Year: 2021

Type: article

Abstract: Inflammation in the brain caused by infections lead to seizures and other neurological symptoms. But the microbial products that induce seizures as well as the host pathways downstream of these factors are largely unknown.

Source: mBio

DOI: 10.1128/mbio.01331-21

Authors: Taylor G. Glausen, Gabriela L. Carrillo, Richard M. Jin, Jon P. Boyle, Jeroen P. J. Saeij, Elizabeth A. Wohlfert, Michael A. Fox, Ira J. Blader

Institutions: University at Buffalo, State University of New York, Virginia Tech, University of Pittsburgh, University of California, Davis, Carilion Clinic

Language: English

Topic: Toxoplasma gondii Research Studies

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: National Institutes of Health, National Institute of Allergy and Infectious Diseases, National Institute of Neurological Disorders and Stroke

Awards: Toxoplasma induces phagocytosis of perisomatic inhibitory synapses, G4190365308, G9000053753

OpenAlex ID: W3174785217

FWCI: 0.659

Cites: 74

Cited by: 9

Related to: 10