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Epigenomic Landscape of Lyme Disease Spirochetes Reveals Novel Motifs

Year: 2021
Type: article
Abstract: The principal causative agent of Lyme disease in humans in the United States is Borrelia burgdorferi , while B. burgdorferi , B. afzelii , and B. garinii , collectively members of the Borrelia burgdorferi sensu lato species complex, cause Lyme disease in Europe and Asia. Two plasmid-encoded restriction/modification systems have been shown to limit the genetic transformation of B. burgdorferi type strain B31 with foreign DNA, but little is known about the restriction/modification systems of other Lyme disease Borrelia bacteria.
Source: mBio
DOI: 10.1128/mbio.01288-21
Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rocky Mountain Laboratories, Czech Academy of Sciences, University of South Bohemia in České Budějovice, Institute of Parasitology, Czech Academy of Sciences, Biology Centre
Language: English
Subfield: Parasitology
Open Access status: gold
Estimated APC paid: $3,900
OpenAlex ID: W3175347222
FWCI: 1.245
Cites: 95
Cited by: 7
Related to: 10