Work

Efficient antigen cross-presentation through coating conventional aluminum adjuvant particles with PEI.

Year: 2021

Type: article

Abstract: nanoparticles. Here we found that coating conventional aluminum adjuvants with polyethyleneimine (PEI) could enhance antigen cross-presentation of DCs (dendritic cells) in vitro and in vivo. PEIs exerted differential effects on antigen cross-presentation. These findings provided an alternative approach to promote the rapid translation of alumina nanoparticles adjuvants into clinical application.

Source: PubMed

Authors: Hongyan Ren, Yongbin Mou, Lin Lin, Lixin Wang, Hongming Hu

Institutions: Nanjing University of Chinese Medicine, Providence Portland Medical Center, Nanjing University, Southeast University

Language: English

Topic: Immunotherapy and Immune Responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3175688037

FWCI: 0.183

Cites: 38

Cited by: 2

Related to: 10