Work

Straightforward synthesis of cytosporone analogs AMS35AA and AMS35BB

Year: 2021

Type: article

Abstract: Cytosporones, a class of octaketide resorcinolic lipids, have drawn the attention of researchers for exhibiting a number of notable biological properties. Herein, we describe routes to synthesize the bioactive synthetic resorcinolic lipids AMS35AA and AMS35BB with excellent overall yields using 3,5-dimethoxybenzoic acid as the starting material. The methods proved remarkably efficient to achieve the target compounds and comprise the synthesis of AMS35AA catalyzed by ascorbic acid (vitamin C).

Source: Anais da Academia Brasileira de Ciências

DOI: 10.1590/0001-3765202120201347

Authors: NEIMAR VITOR, ALISSON MEZA, ROBERTO S. GOMES, JAMAL RAFIQUE, DÊNIS P. DE LIMA, ADILSON BEATRIZ

Institutions: Universidade Federal de Mato Grosso do Sul, Centro Universitário Anhanguera, North Dakota State University

Language: Portuguese

Topic: Organic Chemistry Synthesis Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W3176040186

FWCI: 0.495

Cites: 20

Cited by: 5

Related to: 10