Year: 2021
Type: article
Abstract: The Adolescent Brain Cognitive Development (ABCD) Study is the largest single-cohort prospective longitudinal study of neurodevelopment and children's health in the United States. A cohort of n = 11,880 children aged 9-10 years (and their parents/guardians) were recruited across 22 sites and are being followed with in-person visits on an annual basis for at least 10 years. The study approximates the US population on several key sociodemographic variables, including sex, race, ethnicity, household income, and parental education. Data collected include assessments of health, mental health, substance use, culture and environment and neurocognition, as well as geocoded exposures, structural and functional magnetic resonance imaging (MRI), and whole-genome genotyping. Here, we describe the ABCD Study aims and design, as well as issues surrounding estimation of meaningful associations using its data, including population inferences, hypothesis testing, power and precision, control of covariates, interpretation of associations, and recommended best practices for reproducible research, analytical procedures and reporting of results.
Source: NeuroImage
Authors: Anthony Steven Dick, Daniel A. Lopez, Ashley L. Watts, Steven Heeringa, Chase Reuter, Hauke Bartsch, Chun Chieh Fan, David N. Kennedy, Clare Palmer, Andrew Marshall, Frank Haist, Samuel Hawes, Thomas E. Nichols, Deanna M. Barch, Terry L. Jernigan, Hugh Garavan, Steven Grant, Vani Pariyadath, Elizabeth Hoffman, Michael Neale, Elizabeth A. Stuart, Martin P. Paulus, Kenneth J. Sher, Wesley K. Thompson
Institutions: Florida International University, University of Rochester Medicine, University of Rochester, University of Missouri, University of Michigan, Institute for Social Research, University of California San Diego, Haukeland University Hospital, University of Massachusetts Chan Medical School, University of Southern California, Children's Hospital of Los Angeles, University of Oxford, Washington University in St. Louis, University of Vermont, National Institutes of Health, National Institute on Drug Abuse, Virginia Commonwealth University, Johns Hopkins University, Laureate Institute for Brain Research
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,300
Awards: G1020259976, G1058358382, G1436251778, G1510635755, G1569016918, G1586463187, G1742849658, G2715786902, G2735337927, G2754895010, G2998093352, G3305455594, G343603955, G3438786812, G3563224455, G3738900353, G3755973507, G4066048162, G4180929035, G4241744443, G469525291, G5002640097, G5081895789, G5139799579, G5976565686, G687916792, G6887863799, G6922259526, G6983123888, G7271102572, G7652160222, G771167098, G815084465, G8281824583, G8679417706, G8762821959, G8865478933, G9000006386, G9000008241, G9000034221, G9000042425, G9000046731, G9000061868, G9000108491, G9000112882, G9000113866, G9000163168, G9000202101, G9000205938, G9000241459, G9000286149, 9/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT U MICHIGAN, 17/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UCLA, 8/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT CHLA, 6/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT OHSU, 21/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT WUSTL, 2/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT UMB, G923039674
OpenAlex ID: W3176511645