Progression Rate From Intermediate Hyperglycemia to Diabetes Mellitus According to the Different Cut Off Levels of Fasting Plasma Glucose
Year: 2020
Type: conference-paper
Abstract: We estimated the risk of type II diabetes mellitus (T2DM) from different cut-off thresholds of fasting plasma glucose (FPG) used to define prediabetic state. We conducted MEDLINE and Embase literature searches from inception to October 2019 and extracted frequency data on different cut-off levels of FPG for risk of progression to T2DM. Compared to FPG < 100 mg/dl, the relative risk (RR) of T2DM progression was 3.87 (95% CI: 3.74, 4.00) in people with 100 to 109 mg/dl and 13.14 (95% CI: 12.74, 13.56) in people with FPG 110 to 125 mg/dl. Compared to FPG 100 to 109 mg//dl, RR of T2DM progression was 3.39 (95% CI: 3.30, 3.48) in people with FPG 110 to 125 mg/dl. In conclusion, there is an increased risk of T2DM for all FPG cut-offs defining the prediabetic state.
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Mahidol University
OpenAlex ID: W3177349304
