The Effect of Stress on Gastrointestinal Physiology in Irritable Bowel Syndrome
Year: 2012
Type: article
Abstract: Stress is an acute threat to the homeostasis of an organism by events in the outside world and evokes adaptive responses to preserve the stability of the internal environment. This adaptation can be carried out by means of alterations in HPA axis hormones, the autonomic nervous system, metabolic and immune systems. However, chronic stress can lead to changes in adaptation system and cause a functional disease such as irritable bowel syndrome (IBS). In fact, stress plays an important role in the development and exacerbations of IBS symptoms and it has been postulated that stress have an effect on the pathophysiology of IBS, including an increase in visceral perception, alterations in gastrointestinal motility and increased intestinal permeability. Therefore, Therapeutic approaches targeting stress management could be of great benefit for patients with irritable bowel syndrome. (Korean J Med 2012;82:164-169) Keywords: Stress; Irritable bowel syndrome; Permeability; Motility; Hypersensitivity ì¤ì¬ ë¨ì´: ì¤í¸ë ì¤; ê³¼ë¯¼ì± ì¥ì¦íêµ°; ì¥í¬ê³¼ë; ì¥ì´ë; ë´ì¥ê³¼ë¯¼ì±ì±
Source: Korean Journal of Medicine
Author: Jungho Park
Institutions: Kangbuk Samsung Hospital, Sungkyunkwan University
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W2170493155