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Manganese-induced reactive oxygen species activate IκB kinase to upregulate YY1 and impair glutamate transporter EAAT2 function in human astrocytes in vitro

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Year: 2021
Type: article
Source: NeuroToxicology
DOI: 10.1016/j.neuro.2021.07.004
Authors: Asha Rizor, Edward Pajarillo, Ivan Nyarko-Danquah, Alexis Digman, Leyah Mooneyham, Deok-Soo Son, Michael Aschner, Eunsook Lee
Institutions: Florida Agricultural and Mechanical University, Meharry Medical College, Albert Einstein College of Medicine, Sechenov University
Language: English

Topic: Heavy Metal Exposure and Toxicity
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of Environmental Health Sciences, National Institute on Minority Health and Health Disparities
Awards: Mechanism of manganese-induced impairment of astrocytic glutamate transporters, Roles of proinflammatory chemokines linking obesity and breast cancer, Genetic Modulation of MeHg-Induced Oxidative Stress in the Developing Brain, FAMU Center for Health Disparities Research, Mechanisms of Manganese Neurotoxicity, Mechanisms associated with neuroprotection from Mn-induced neurotoxicity.
OpenAlex ID: W3184226929
FWCI: 0.792
Cites: 56
Cited by: 21
Related to: 10
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