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Lower body negative pressure reduces jugular and portal vein volumes and counteracts the elevation of middle cerebral vein velocity during long-duration spaceflight

Year: 2021
Type: article
Abstract: Microgravity-induced fluid shifts markedly enlarge jugular and portal veins and increase cerebral vein velocity. These findings demonstrate a marked flow engorgement at neck and splanchnic levels and may suggest compression of the cerebral veins by the brain tissue in space. LBNP (-25 mmHg for 30 min) returns these changes to preflight levels and, thus, reduces the associated flow and tissue disturbances.
DOI: 10.1152/japplphysiol.00231.2021
Authors: P. Arbeille, K. A. Zuj, B. R. Macias, D. J. Ebert, S. S. Laurie, A. E. Sargsyan, D. S. Martin, S. M. C. Lee, S. A. Dulchavsky, M. B. Stenger, A. R. Hargens
Institutions: Université de Tours, Johnson Space Center, KBR (United States), Henry Ford Hospital, UC San Diego Health System, University of California San Diego, University of California San Diego Medical Center
Language: English
Subfield: Physiology
Field: Medicine
Open Access status: green
OpenAlex ID: W3184721699
FWCI: 3.137
Cites: 31
Cited by: 43
Related to: 10