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Single Agent and Synergistic Combinatorial Efficacy of First-in-Class Small Molecule Imipridone ONC201 in Hematological Malignancies In Vitro and In Vivo through Apoptosis Via the Integrated Stress Response Pathway

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Year: 2017
Type: article
Source: Blood
DOI: 10.1182/blood.v130.suppl_1.3842.3842
Authors: Varun V. Prabhu, Mala K. Talekar, Amriti R. Lulla, C. Leah B. Kline, Lanlan Zhou, Junior Hall, A. Pieter J. van den Heuvel, David T. Dicker, Stephan A. Grupp, Mathew J. Garnett, Ultan McDermott, Cyril H. Benes, Jeffrey J. Pu, David F. Claxton, Wolfgang Oster, Joshua E. Allen, Wafik S. El‐Deiry
Institutions: Oncoceutics (United States), Children's Hospital of Philadelphia, Fox Chase Cancer Center, Pennsylvania State University, Wellcome Sanger Institute, Massachusetts General Hospital, Penn State Cancer Institute
Language: English

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W3185106946
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Related to: 20
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