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Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery

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Year: 2021
Type: review
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.1c00895
Authors: Guoqiang Dong, Yu Ding, Shipeng He, Chunquan Sheng
Institutions: Second Military Medical University, Shanghai Medical College of Fudan University, Fudan University, Huashan Hospital, State Key Laboratory of Medical Neurobiology, Frontiers Center for Brain Science of the Ministry of Education, Shanghai University
Language: English

Topic: Protein Degradation and Inhibitors
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Ministry of Science and Technology of the People's Republic of China
Awards: G5207590768, G6125044659, G6519793249, G8070806108
OpenAlex ID: W3186572052
FWCI: 5.318
Cites: 78
Cited by: 369
Related to: 10
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