Work

Defining and Manipulating B Cell Immunodominance Hierarchies to Elicit Broadly Neutralizing Antibody Responses against Influenza Virus

Year: 2020

Type: article

Source: Cell Systems

DOI: 10.1016/j.cels.2020.09.005

Authors: Assaf Amitai, Maya Sangesland, Ralston M. Barnes, Daniel Rohrer, Nils Lonberg, Daniel Lingwood, Arup K. Chakraborty

Institutions: Massachusetts Institute of Technology, Ragon Institute of MGH, MIT and Harvard, Bristol-Myers Squibb (United States)

Language: English

Topic: Influenza Virus Research Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Science Foundation, Harvard University, National Institutes of Health, National Institute on Drug Abuse, National Institute of Allergy and Infectious Diseases

Awards: G1263100650, CDRH3-independent B cell stimulation to selectively expand VRC01 lineages from a fully humanized immunoglobulin repertoire, A genetic template for generating universally protective responses to influenza, Innate-like BCR activity as a template for universal vaccination against influenza virus, Defining and Exploiting a Genetic Template for an HIV Vaccine, Triggering germline-encoded broadly neutralizing antibody responses against influenza virus, G5385058180, Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro, Systemic coordination of pro-inflammatory immune reactions through dendritic cell-restricted sIL6R biogenesis

OpenAlex ID: W3092608325

FWCI: 6.625

Cites: 96

Cited by: 70

Related to: 10