Charge substitutions at the voltage-sensing module of domain III enhance actions of site-3 and site-4 toxins on an insect sodium channel
Year: 2021
Type: article
Authors: Qing Zhu, Yuzhe Du, Yoshiko Nomura, Rong Gao, Zixuan Cang, Guo-Wei Wei, Dalia Gordon, Michael Gurevitz, James Groome, Ke Dong
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Awards: G3021184089, Synergistic integration of topology and machine learning for the predictions of protein-ligand binding affinities and mutation impacts, Kinetics-Driven Drug Discovery Using Persistent Homology, Rare-Event Molecular Dynamics and Experimental Data, Geometric and Topological Modeling and Computation of Biomolecular Structure, Function, and Dynamics, High-resolution insights into insecticide interactions with voltage-gated sodium channels, G8403996678
OpenAlex ID: W3190727443
