Year: 2015
Type: article
Abstract: Cachexia-anorexia syndrome, characterized by anorexia and loss of adipose tissue and skeletal muscle mass, is common feature in majority of patients with cancer, especially in cancer localized in gastrointestinal tract.Malnutrition is recognized as a negative prognostic factor in patients with colorectal cancer.Malnutrition in cancer patients reduces response to specific oncological therapy, slows down recovery after surgical treatment, leads to impairement of quality of life and decreases survival.It is considered that developement of cancer cachexia is a multifactorial process, however inflammation plays a major role.Therefore, targeting inflammation may represent an effective strategy to prevent/treat cachexia.Treatment should be patient-tailored and based on a multimodal approach.
Authors: Željko Krznarić, Ana Kunović
Language: Croatian
Subfield: Physiology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3192069920