Year: 2021
Type: article
Abstract: Controlled breakdown has recently emerged as a highly appealing technique to fabricate solid‐state nanopores for a wide range of biosensing applications. This technique relies on applying an electric field of approximately 0.4–1 V nm−1 across the membrane to induce a current, and eventually, breakdown of the dielectric. Although previous studies have performed controlled breakdown under a range of different conditions, the mechanism of conduction and breakdown has not been fully explored. Here, electrical conduction and nanopore formation in SiNx membranes during controlled breakdown is studied. It is demonstrated that for Si‐rich SiNx, oxidation reactions that occur at the membrane‐electrolyte interface limit conduction across the dielectric. However, for stoichiometric Si3N4 the effect of oxidation reactions becomes relatively small and conduction is predominately limited by charge transport across the dielectric. Several important implications resulting from understanding this process are provided which will aid in further developing controlled breakdown in the coming years, particularly for extending this technique to integrate nanopores with on‐chip nanostructures.
Source: Small
Authors: Jasper P. Fried, Jacob L. Swett, Binoy Paulose Nadappuram, Aleksandra Fedosyuk, Pedro Miguel Sousa, Dayrl P. Briggs, Aleksandar P. Ivanov, Joshua B. Edel, Jan A. Mol, James R. Yates
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $5,000
Funders: U.S. Department of Energy, UK Research and Innovation, Royal Academy of Engineering, European Commission, Office of Science, Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council, Fundação para a Ciência e a Tecnologia, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, H2020 European Research Council
Awards: A HIGH THROUGHPUT SCREEN TO IDENTIFY STRATEGIES TO STIMULATE RECOGNITION OF BACTERIA BY THE INNATE IMMUNE SYSTEM, G1483381719, G3029852638, Single Molecule Nanoscale Sensors for Improved Therapies and Diagnostics, G3147037691, Detecção e Caracterização de Nanopartículas Usando Nanoporos de Estado Sólido: Uma Abordagem Única Molécula, High throughput multiplexed trace-analyte screening for diagnostics applications, G434337789, G4646689544, G5454278309, New generation of biosensors using nanopore extended Field Effect Transistors (NexFET), Microbiologia Molecular, Estrutural e Celular - – Instituto de Tecnologia Química e Biológica António Xavier, G6194379119, Selective Nanobrush Sensors (SNS) for Label-free Diagnosis of Neurodegenerative Disorders, G6450236195, Microbiologia Molecular, Estrutural e Celular - – Instituto de Tecnologia Química e Biológica António Xavier, G8191554803, G8231754083, Ultrafast Optoelectronic Nanoscopy of Biological and Optoelectronic Systems, G8380321507
OpenAlex ID: W3149655836