Work

Sex- and Gender-related Issues of Gut Microbiota in Gastrointestinal Tract Diseases

Year: 2021

Type: article

Abstract: The distribution of gut microbiota varies according to age and sex.Gut microbiota are known to contribute to gastrointestinal (GI) diseases such as irritable bowel syndrome, inflammatory bowel disease, and colon cancer; however, the exact etiology remains elusive.Sex hormone such as estrogen and testosterone control the microbiota mainly due to different effect on the immunity.In addition, the diet depending on gender also affect the gut microbiota.Furthermore, the metabolism of estrogen and androgen was reported to be related to the gut microbiome.However, there have been few comprehensive review articles regarding the effect of microbiota on GI diseases.In this review, the factors which affect the gut microbiota and the interplay of microbiota and GI diseases in terms of sex-and gender differences were briefly summarized.(

Source: Korean Journal of Gastroenterology

DOI: 10.4166/kjg.2021.409

Author: Nayoung Kim

Institutions: Seoul National University, Seoul National University Bundang Hospital

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $7