Year: 2021
Type: article
Abstract: Paradoxical lucidity in dementia is a clinically significant but understudied phenomenon. A provisional definition was proposed by the 2018 National Institute on Aging expert workshop and published in Alzheimer's and Dementia. However, several conceptual features of this definition remain vague, creating barriers to robust clinical research. Here, we critically analyze the provisional definition and present a refined definition that can be applied in clinical research. The refined definition is based on an analytic process our research group recently undertook to operationalize paradoxical lucidity for our own study protocol. Our goal is to facilitate debate and potentially harmonize interpretations of paradoxical lucidity among research groups.
Source: Alzheimer s & Dementia
DOI: 10.1002/alz.12424
Institutions: George Mason University, University of Pennsylvania
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,000
Funder: National Institute on Aging
Awards: Study of Cognitive Symptoms and Future Time Perspective in Preclinical Alzheimer's Disease, UNDERSTANDING HOW THE STUDY PARTNER REQUIREMENT IMPACTS THE DISCOVERY AND TRANSLATION OF PRECLINICAL ALZHEIMERS DISEASE, Caregivers' Experiences with and Perspectives on Communication with Persons with Dementia, Penn Artificial Intelligence and Technology Collaboratory for Healthy Aging, Penn Alzheimer's Disease Research Center (ADRC)
OpenAlex ID: W3192960411