Work

Structure‐guided identification of a peptide for bio‐enabled gold nanoparticle synthesis

Year: 2021

Type: article

Abstract: In this study, we show that maltose-binding protein (MBP) is capable of facilitating stable gold nanoparticle synthesis, and a structure of MBP in the presence of gold ions was determined by X-ray crystallography. Using this high-resolution structure of gold ion bound MBP, a peptide (AT1) was selected and synthesized and was shown to also aid in the synthesis of stable gold nanoparticles under similar experimental conditions to those used for protein facilitated synthesis. This structure-based approach represents a new potential method for the selection of peptides capable of facilitating stable nanoparticle synthesis.

Source: Biotechnology and Bioengineering

DOI: 10.1002/bit.27927

Authors: Amar Thaker, Luqmanal Sirajudeen, Chad R. Simmons, Brent L. Nannenga

Institution: Arizona State University

Language: English

Topic: Gold and Silver Nanoparticles Synthesis and Applications

Subfield: Electronic, Optical and Magnetic Materials

Field: Materials Science

Domain: Physical Sciences

Open Access status: bronze

Funder: Air Force Office of Scientific Research

Award: G616170257