Work

Deciphering Microbial Metal Toxicity Responses via Random Bar Code Transposon Site Sequencing and Activity-Based Metabolomics

Year: 2021

Type: article

Abstract: Studying microbial interactions with their environment can lead to a deeper understanding of biological molecular mechanisms. In the manuscript, two global techniques, RB-TnSeq and activity metabolomics, were successfully used to probe the interactions between a metal-resistant microorganism, Pantoea sp. strain MT58, and metals contaminating a site where the organism can be located.

Source: Applied and Environmental Microbiology

DOI: 10.1128/aem.01037-21

Authors: Michael P. Thorgersen, Jingchuan Xue, Erica L. W. Majumder, Valentine V. Trotter, Xiaoxuan Ge, Farris L. Poole, Trenton K. Owens, Lauren M. Lui, Torben N. Nielsen, Adam P. Arkin, Adam M. Deutschbauer, Gary Siuzdak, Michael W. W. Adams

Institutions: University of Georgia, Scripps Research Institute, Lawrence Berkeley National Laboratory

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: U.S. Department of Energy, Office of Science, Biological and Environmental Research, Lawrence Berkeley National Laboratory

Awards: G1079818582, G1143651532, G1286236842, G1337544421, G223002938, G3083819904, G42916606, G4501827968, G498139845, G6652958823, G7354628648, G7787287669, G969889393

OpenAlex ID: W3193973428

FWCI: 0.706

Cites: 68

Cited by: 7

Related to: 10