Year: 2021
Type: article
Abstract: Through genetic fusion with a transduction domain, the recombinant stimulator interferon genes (STING) can encapsulate cyclic dinucleotides (CDNs) and spontaneously penetrate tumor cells. This STING-based protein delivery platform represents a substantial departure from the status quo because it can serve as a functional vehicle to restore the STING signaling in immunosuppressive tumors with impaired STING expression. This is reported by Jiahe Li and co-workers in article number 2100066.
Source: Advanced Therapeutics
Authors: Xin Sun, Yun Ni, Yanpu He, Mengdi Yang, Tetsuo Tani, Shunsuke Kitajima, David A. Barbie, Jiahe Li
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W3194412293