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Human-relevant mechanisms and risk factors for TAK-875-Induced liver injury identified via a gene pathway-based approach in Collaborative Cross mice

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Year: 2021
Type: article
Source: Toxicology
DOI: 10.1016/j.tox.2021.152902
Authors: Merrie Mosedale, Yanwei Cai, J. Scott Eaddy, Patrick J. Kirby, Francis S. Wolenski, Yvonne Dragan, William Valdar
Institutions: University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center
Language: English

Topic: Drug-Induced Hepatotoxicity and Protection
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Takeda Pharmaceuticals International, National Institute of General Medical Sciences
Awards: G3981560230, Statistical Modeling of Multiparental and Genetic Reference Populations
OpenAlex ID: W3194699305
FWCI: 3.91
Cites: 63
Cited by: 19
Related to: 10
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