Advancing a temporal framework for understanding the biology of nonsuicidal self- injury: An expert review
Year: 2021
Type: review
Abstract: Nonsuicidal self-injury (NSSI) is a serious clinical problem, particularly for adolescents and young adults. NSSI is a complex behavior that emerges through the intersecting effects of social, psychological, and biological mechanisms. Although the social and psychological contributions to risk for developing NSSI are relatively well understood and have guided the development of effective psychosocial treatments for self-injury, the biological mechanisms underlying NSSI have just begun to come to light. To evaluate and categorize the biological research conducted on the topic of NSSI, we propose a model that distinguishes between trait and state markers. According to this model, risk factors and mechanisms involved in NSSI can be distinguished into both trait and state factors. We review the existing evidence on distal biological traits (predictors) of NSSI, proximal biological traits (correlates) of NSSI, and biological states directly preceding or following NSSI. We conclude by providing recommendations for future research on the neurobiology of NSSI.
Institutions: University of Bern, University Hospital Heidelberg, Harvard University, University of Minnesota, University of Cologne, Heidelberg University, University Hospital Cologne, Universität Ulm, Medical University of Vienna, Victoria University of Wellington, Central Institute of Mental Health, Medizinische Fakultät Mannheim, University of Utah
Language: English
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: hybrid
Estimated APC paid: $4,340
Awards: A Longitudinal Study Examining Three RDoC Constructs in Adolescents with Non-Suicidal Self-Injury, Identifying Biological Signatures of N-acetylcysteine for Non-Suicidal Self-Injury in Adolescents, Developmental Trajectories of Brain Network Strength and Flexibility: Relationship to Risk, Onset and Course of Depression and Self-Harm in Youth
OpenAlex ID: W3195634650