Work

Memory CD8 + T cells mediate early pathogen-specific protection via localized delivery of chemokines and IFNγ to clusters of monocytes

Year: 2021

Type: article

Abstract: Protection in vaccinated hosts occurs quickly upon pathogen-specific memory CD8 + T cell–mediated activation of myeloid cells.

Source: Science Advances

DOI: 10.1126/sciadv.abf9975

Authors: Marie Boutet, Zachary Benet, Erik Guillen, Caroline Koch, Saidi M’Homa Soudja, Fabien Delahaye, David Fooksman, Grégoire Lauvau

Institutions: Albert Einstein College of Medicine, Institut Pasteur de Lille

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,500

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: Enhancing Pathogen-specific Memory CD8+ T cell Responses in Vivo, Einstein Postbaccalaureate Research Education Program, Contribution of ASC Dynamics to Survival within the Bone Marrow, Enhancing Pathogen-Specific Memory CD8+ T cell Responses In Vivo, Medical Scientist Training Program, G9000125956, Cancer Center Support Grant, CD138 Regulates Competition of Antibody Secreting Cells for Survival

OpenAlex ID: W3196334591

FWCI: 0.652

Cites: 67

Cited by: 18

Related to: 10