Year: 2021
Type: book-chapter
Abstract: Clinical research involving child participants frequently raises both legal and ethical concerns that researchers, clinicians, and parents must navigate to pursue relevant pediatric-centered investigation in health and particularly in cancer care. The foundational ethico-legal principles governing research participation provide the necessary frameworks with which to evaluate how emerging genetic technologies can serve current and future childhood cancer research. Taking the best interests of the child as the primary consideration in all decisions affecting a child, this chapter explores issues regarding consent/assent and return of results in pediatric oncology research. With a primary focus on Canada, the USA, and Europe, we examine the issues presented by the use of next-generation sequencing, pharmacogenomics, and biobanking and data sharing in international consortia.
Source: Springer eBooks
Language: English
Topic: Ethics in Clinical Research
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: G6055310640, G8472241119
OpenAlex ID: W3196580736