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Guidance on the critical shortage of sodium citrate coagulation tubes for hemostasis testing

Year: 2021
Type: article
Abstract: Recent manufacturing problems and increased utilization has created a shortage of 3.2% sodium citrate blood collection tubes used for coagulation testing, causing stakeholders such as hospitals, clinics and laboratories, to find suitable alternatives. Considerations for in-house citrate blood collection tube preparations or purchasing commercial products from unknown manufacturing sources is of particular concern to laboratories that perform coagulation testing. It is well recognized that variability exists between citrate blood collection tube manufacturers, thereby making any transition to new blood collection methods more challenging than simply switching to a new source. This document provides provisional guidance for validating alternative sources of sodium citrate blood collection tubes (commercial or in-house preparations) prior to clinical implementation.
DOI: 10.1111/jth.15514
Authors: Robert C. Gosselin, Annette Bowyer, Emmanuel J. Favaloro, Jill M. Johnsen, Giuseppe Lippi, Richard A. Marlar, Keith Neeves, Marian A. Rollins‐Raval
Institutions: UC Davis Health, University of California, Davis, Royal Hallamshire Hospital, Westmead Hospital, NSW Health Pathology, University of Washington, Bloodworks Northwest, University of Verona, University of New Mexico, University of Colorado Anschutz, University of Colorado Denver
Language: English
Subfield: Physiology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $3,500
OpenAlex ID: W3197467153
FWCI: 2.667
Cites: 15
Cited by: 25
Related to: 10