Year: 2014
Type: article
Study design: Clinical Trial
Abstract: Objective: To analyze the safety and efficacy of device closure of secundum atrial septal defect in children ≤ 5years of age.Study Design: Quasi-experimental study.Place and Duration of Study: The study was conducted at Armed Forces Institute of Cardiology / NationalInstitute of Heart Diseases Rawalpindi, Pakistan from Dec 2010 - Dec 2012.Patients and Method: Forty eight patients ≤ 5 years of age underwent transcatheter closure of secundum ASDduring two years. All patients were evaluated with 2-D echocardiography before the procedure. The sizingballoon was used in 6% and general anaesthesia was given in 83% (n=40) of patients.Results: Ninety seven point nine percent (47/48) had successful closure of ASD. The mean age was 4.1 ± .68 years(range 2.5-5 years) and 58.4% (28/48) were females. The defect size and occluders used were between 5-20 mm(mean 12 ± 3.5) and 8-22 mm (mean 15 ± 3.9) respectively, three patients had simultaneous procedures includingpulmonary valvuloplasty in two and percutaneous transmitral commissurotomy (PTMC) in one. The majorcomplications remained 2% (1/48) which included device embolization just after release of device while minorcomplication rate was 12.5%. The median procedure time was 30 min (15-100 min) and median fluoroscopic timewas 6 min (1.50-45 min). There was no emergency surgical exploration or death during this period.Conclusion: Transcatheter device closure of suitable secundum atrial septal defect is effective and safe in youngchildren in skilled and professional hands.
Institution: Pakistan Army
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W3197467635