Two forms of short-interval intracortical inhibition in human motor cortex
Year: 2021
Type: article
Abstract: BACKGROUND: Pulses of transcranial magnetic stimulation (TMS) with a predominantly anterior-posterior (AP) or posterior-anterior (PA) current direction over the primary motor cortex appear to activate distinct excitatory inputs to corticospinal neurons. In contrast, very few reports have examined whether the inhibitory neurons responsible for short-interval intracortical inhibition (SICI) are sensitive to TMS current direction. OBJECTIVES: ). METHODS: . RESULTS: . CONCLUSIONS: . The difference is behaviourally relevant since the pathways are controlled differently during volitional contraction. The results may explain some previous pathological data and open the possibility of testing whether these pathways are differentially recruited in a range of tasks.
Source: Brain stimulation
Institutions: Chang Gung University, Chang Gung Memorial Hospital, Taoyuan Chang Gung Memorial Hospital, Linkou Chang Gung Memorial Hospital, UCL Queen Square Institute of Neurology, University College London, Fondazione Santa Lucia, University of Cagliari, University of California San Diego, Università Campus Bio-Medico, Al-Azhar University
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,310
Funder: Medical Research Council
OpenAlex ID: W3198643175