Work

African Swine Fever Virus Bearing an I226R Gene Deletion Elicits Robust Immunity in Pigs to African Swine Fever

Year: 2021

Type: article

Abstract: of its virulent parental virus. Furthermore, the nucleic acid of the gene-deleted virus and its virulent parental virus was rarely detected from oral or anal swabs. Viruses could not be detected in any tissues after necropsy when viremia became negative, indicating that robust immunity was achieved. Therefore, SY18ΔI226R is a novel, ideal, and efficacious vaccine candidate for genotype II ASF.

Source: Journal of Virology

DOI: 10.1128/jvi.01199-21

Authors: Yanyan Zhang, Junnan Ke, Jingyuan Zhang, Jinjin Yang, Huixian Yue, Xintao Zhou, Yu Qi, Rongnian Zhu, Faming Miao, Qian Li, Fei Zhang, Ying Wang, Xun Han, Lijuan Mi, Jinmei Yang, Shoufeng Zhang, Teng Chen, Rongliang Hu

Institutions: Chinese Academy of Agricultural Sciences, Jilin Agricultural University

Language: English

Topic: Animal Disease Management and Epidemiology

Subfield: Agronomy and Crop Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: hybrid

Funder: National Natural Science Foundation of China

Award: G3261162415

OpenAlex ID: W3198706324

FWCI: 20.85

Cites: 43

Cited by: 96

Related to: 10