Isotopic abundance and chemical purity analysis of stable isotope deuterium labeled Sudan I
Year: 2014
Type: article
Abstract: It is important that to analysis of the isotopic abundance and chemical purity of Sudan I-D5, which is the internal standard of isotope dilution mass spectrometry. The isotopic abundance of Sudan I-D5 is detected by “mass cluster” classification method and LC-MS. The repeatability and reproducibility experiments were carried out by using different mass spectrometers and different operators. The RSD was less than 0.1%, so the repeatability and reproducibility were satisfactory. The accuracy and precision of the isotopic abundance analysis method was good with the results of F test and t test. The high performance liquid chromatography (HPLC) had been used for detecting the chemical purity of Sudan I-D5 as external standard method.
Authors: Cai Yin-ping, Wen Lei, Bo Zheng, Du Xiaoning
Institution: Shanghai Research Institute of Chemical Industry
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W3198945586