Improving rigor and reproducibility in nonhuman primate research
Year: 2021
Type: review
Abstract: Nonhuman primates (NHPs) are a critical component of translational/preclinical biomedical research due to the strong similarities between NHP and human physiology and disease pathology. In some cases, NHPs represent the most appropriate, or even the only, animal model for complex metabolic, neurological, and infectious diseases. The increased demand for and limited availability of these valuable research subjects requires that rigor and reproducibility be a prime consideration to ensure the maximal utility of this scarce resource. Here, we discuss a number of approaches that collectively can contribute to enhanced rigor and reproducibility in NHP research.
Source: American Journal of Primatology
DOI: 10.1002/ajp.23331
Institutions: University of California, Davis, Emory National Primate Research Center, University of Washington, University of Wisconsin System, University of Wisconsin–Madison, Tulane University, Wake Forest University Health Sciences, Wake Forest University, Oregon National Primate Research Center, Oregon Health & Science University, Vaccine and Gene Therapy Institute
Language: English
Subfield: Small Animals
Field: Veterinary
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,700
Awards: Computational and Circuit Mechanisms Underlying Rapid Learning, G159247434, G2069825596, G2462596300, G2503872370, G278379982, G3226510573, G4095048254, Temporally coordinated activity in the primate hippocampus supporting memory formation, Washington National Primate Research Center, Wisconsin National Primate Research Center Support, California National Primate Research Center, The Southwest National Primate Research Center, Tulane National Primate Research Center, Support for National Primate Research Center, Emory National Primate Research Center
OpenAlex ID: W3199195783