Work

Cellular redox state constrains serine synthesis and nucleotide production to impact cell proliferation

Year: 2019

Type: article

Source: Nature Metabolism

DOI: 10.1038/s42255-019-0108-x

Authors: Frances F. Diehl, Caroline A. Lewis, Brian P. Fiske, Matthew G. Vander Heiden

Institutions: Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology, Whitehead Institute for Biomedical Research, Dana-Farber Cancer Institute

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Howard Hughes Medical Institute, U.S. Department of Health and Human Services, National Institute of Mental Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: G1641717585, Understanding the role of serine metabolism in cancer, G418671524, The Effect of Serine Source on Nucleotide Metabolism in Cancer: Manipulating Environmental Nutrient Availability to Impact Tumor Growth, G4513495860, Regulation of glucose metabolism to allow tumor initiation and growth, Training Program in Mental Health Research, Analysis of cancer cell metabolism in diverse environmental conditions, G55227058, Pre-Doctoral Training in Biological Sciences, G8626984200, Cancer Center Support (Core) Grant, Understanding the role of metabolism in cancer

OpenAlex ID: W2973847049

FWCI: 6.942

Cites: 26

Cited by: 159

Related to: 10