The predictive values of GGT and Hcy in the risk stratifications and prognoses of NSTE-ACS patients.
Year: 2021
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: This research was designed to probe into the predictive value of glutamyltransferase (GGT) and homocysteine (Hcy) in the risk stratifications and prognoses of non-ST segment elevation acute coronary syndrome (NSTE-ACS) patients. METHODS: A total of 182 NSTE-ACS patients treated with percutaneous coronary intervention (PCI) in our hospital from February 2016 to May 2018 were recruited as a patient group (PG). They were followed up for one year, and the occurrences of any major adverse cardiovascular events (MACCE) were recorded. In addition, 90 healthy volunteers were recruited as a normal group (NG) during the same period. The GGT and Hcy expressions in the serum of both groups were tested, and the predictive values of these levels, the patient risk stratification, and the prognoses were analyzed. RESULTS: < 0.05). Our ROC curve analysis indicated that the serum GGT and Hcy levels are diagnostic criteria for predicting whether MACE occurred in NSTE-ACS patients. CONCLUSION: The serum GGT and Hcy levels are positively correlated with the severity of coronary artery disease (CAD) in NSTE-ACS patients. They are independent predictors of adverse prognoses and can help refine the risk stratification management in clinical work.
Source: Europe PMC (PubMed Central)
Authors: Xiaoxia Li, Su Bu, Bin Dong, Yaodong Hu, Luhua Cui, Xiaohua Gao, Donghua Ren, Lixia Qin, Jiawei Wen
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3199982120