Year: 2021
Type: article
Abstract: , implicating this as an immune defense mechanism that broadly enhances antibacterial activity. These results demonstrate that achieving maximal bactericidal activity through NET formation requires macrophages and that accelerated and more robust suicidal NETosis makes neutrophils adept at increasing antibacterial activity, especially when A9 deficient.
Source: Science Advances
Institutions: Vanderbilt University, Vanderbilt University Medical Center
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $4,500
Awards: G1344704808, G2019238319, G3217217337, Vanderbilt Mouse Metabolic Phenotyping Center, Mechanism and function of heme-iron utilization in staphylococcal pathogenesis, G725763919, G836990232, G8434023134, Molecular and Cellular Basis for Digestive Diseases, Vanderbilt Diabetes Research Center, Core Grant in Vision Research, Host-mediated zinc sequestration during Acinetobacter baumannii infection
OpenAlex ID: W3200061555