Work

2-(4-Hydroxyphenyl)benzothiazole dicarboxylate ester TACN chelators for 64 Cu PET imaging in Alzheimer's disease

Year: 2021

Type: article

Abstract: A series of bifunctional chelators (BFCs) with high affinity for amyloid β aggregates, a strong Cu( ii ) chelating ability, and favorable lipophilicity for potential blood–brain barrier penetration are reported.

Source: Dalton Transactions

DOI: 10.1039/d1dt02767k

Authors: Yujue Wang, Truc T. Huynh, Nilantha Bandara, Hong-Jun Cho, Buck E. Rogers, Liviu M. Mirica

Institutions: University of Illinois Urbana-Champaign, Washington University in St. Louis, Hope Center for Neurological Disorders

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Award: Novel Bifunctional Chemical Agents as Theranostic Tools for Amyloid Diseases

OpenAlex ID: W4200165743

FWCI: 1.189

Cites: 49

Cited by: 15

Related to: 10