Work

Co-targeting TGF-β and PD-L1 with radiation therapy: The Goldilocks principle

Year: 2021

Type: article

Abstract: In the current issue of Cancer Cell , Lan et al. 1 demonstrate that a bifunctional fusion protein targeting TGF-β and PD-L1 can synergize with radiation therapy to simultaneously augment tumor control and reduce normal tissue toxicity.

Source: Cell Reports Medicine

DOI: 10.1016/j.xcrm.2021.100406

Authors: Samuel F. Bakhoum, Charles M. Rudin

Institution: Memorial Sloan Kettering Cancer Center

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,200

Funders: National Institutes of Health, National Cancer Institute

Awards: G9000268190, Probing cytosolic nucleic acid sensing pathways in cancer

OpenAlex ID: W3202798748

FWCI: 0.163

Cites: 11

Cited by: 2

Related to: 10