Work

Effect of High-Dose Posaconazole on Serum Levels in Adult Patients with Hematologic Malignancy

Year: 2021

Type: article

Abstract: Posaconazole (POS) appears to have dose-proportional pharmacokinetics; however, there is a paucity of real-life data. We retrospectively evaluated 67 patients with hematologic cancer who had POS dose increases from 300 mg/day to either 400 mg/day ( n = 52) or 300 mg twice daily (BID) ( n = 15) and for whom POS serum levels were measured.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.01230-21

Authors: Adam J. DiPippo, Patrick M. McDaneld, Frank P. Tverdek, Dimitrios P. Kontoyiannis

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3203308490

FWCI: 0.298

Cites: 15

Cited by: 4

Related to: 10